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Epstein–Barr virus nuclear antigen 3
The
Epstein–Barr virus
nuclear
antigen
3
is a
family
of
viral proteins
associated with the
Epstein–Barr
virus
. A
typical
EBV
genome
contains
three such proteins:
EBNA-3A
EBNA-3B
EBNA-3C
These
genes
also
bind
the host
RBP-Jκ
protein
.
EBNA-3C can
recruit
a
ubiquitin ligase
and has been
shown
to
target
cell-cycle
regulators
such as
retinoblastoma protein
.